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Exhibit 10.23

SECOND AMENDMENT TO
LICENSE, DEVELOPMENT AND COMMERCIALIZATION AGREEMENT

THIS SECOND AMENDMENT (“ Second Amendment ”) to the License, Development and Commercialization Agreement dated 12 th of June, 2007 (“ Agreement ”) by and between Cook Incorporated and its Affiliates (“ Cook ”), and Cardica, Inc., and its Affiliates (“ Cardica ”) is made by and between the same two parties on this 19 th day of June, 2009 (“ Second Amendment Effective Date ”). The parties agree as follows:

1.0 All capitalized terms used in this Second Amendment, but not defined herein, shall have the meanings ascribed to them in the Agreement.

2.0 Delete Section 7.1 and replace it with the following paragraphs:

     “ 7.1 Technology Transfer. Upon determination by the Development Committee that a Product is ready for commercialization, or at Cook’s option at any other time, Cook will have the option but not the obligation to manufacture such Product, or to have such Product manufactured by Cardica or a third party designated by Cook with the consent of Cardica, which consent shall not be unreasonably withheld, conditioned or delayed.

 

A.

 

Testing and Development. Cardica will continue to supply to Cook, upon Cook’s request and at a cost of $250.00 per unit, such additional units of the Product over the n


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